Preparation of flocculant PAM solution, prone to clumping but difficult to dissolve, what should be done?
May 27,2024
1) Why is it difficult to dissolve?
Because flocculants are linear polymer compounds, their characteristic is that they are difficult to dissolve and have a long dissolution and maturation time.
2) What are the key factors in solving this problem?
1. Polymer polymerization is difficult to dissolve and needs to be thoroughly and uniformly pre mixed with solvents to prevent clumping and agglomeration.
2. The dissolution and maturation time of polymer is long, and it is necessary to ensure sufficient dissolution and stirring time.
3. The drug is difficult to dissolve, but it is also necessary to prevent the linear structure of the polymer from being damaged, which affects the efficacy of the drug. Therefore, high requirements are placed on the speed and method of stirring
4. Hydrolysis may occur during storage after drug preparation, and the storage requirement for the drug solution is to use it as soon as possible after preparation
5. It is best to control the solvent temperature at 20-30 degrees Celsius, as too low or too high can affect the efficacy of the drug. Too low will increase the difficulty of dissolution and preparation. Excessive height can easily lead to polymer hydrolysis, resulting in the loss of medicinal properties.
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